Endocrine Abstracts

Introduction: Thyroid nodules are very common in the general population (20-75% ultrasound). There are clinical management criteria established by international societies and standardized cytological diagnostic criteria (Bethesda). However, there is still uncertainty in the management of category 5.Objectives: To evaluate the clinical attitude to the cytological diagnosis of Bethesda category 5 (B5) in thyroid fine-needle aspiration cytology (FNA). And s...

Introduction: Ultrasound is the main diagnostic tool for imaging pathology of the thyroid gland. The TI-RADS classification allows the evaluation of a risk of malignancy in the case of thyroid nodules, indicating the need to perform a puncture for a histological study. Bethesda system classifies them according to the cytological malignancy risk. Bethesda category 3 (B3) comprises ‘follicular lesion of undetermined significance’ or ‘atypia of undetermined signifi...

Background: The diabetes type 1 (DM1) is a chronic autoimmune disease, it tends to appear in childhood, its incidence continues to rise and the complications arising from improper care poses serious health problems for those who suffer. LADA diabetes is autoimmune diabetes which appear in adults.Objetive: To describe the characteristics of the new diabetes debut in our environment.Material and methods: We included all patients who ...

Background: In last year, different analogues of very long duration basal insulin have appeared, which favors the flexibility in its use. Both ensure a decrease in the rate of hypoglycemia and improve glycemic control in clinical trials. However, in real practice we have few data in real practice.Objective: To compare the two ultralente insulin analogues in real practice. To analyze if they are cost effective.Material and methods: ...

Objective: Transsphenoidal surgery (TSS) presents the treatment of choice for Cushing’s disease (CD), 95% microadenomas. Remission and recurrence rates vary dependent on tumor size, extension, adenoma visibility on magnetic resonance imaging, and neurosurgical expertise. Remission rates in the postoperative vary between 55 and 85%, with a recurrence of up to 25%. The aim of this study was to describe the rate of remission and recurrence of CD in our midst after TSS, and c...

Acromegaly is caused by excessive growth hormone (GH) secretion from pituitary adenomas. Transphenoidal surgery is the first-choice treatment, but new drug therapies (e.g. somatostatin analogs, SSA) offer promising avenues for medical treatment. Complementary diagnostic tools may assist this strategy, helping to refine drug choice. Here, we investigate the associations between postsurgical radiological features and molecular phenotype of pituitary tumors from acromegalic patie...

Introduction: Eating disorders (ED) are prevalent psychiatric conditions with significant nutritional implications, posing a risk of life-threatening illness for patients. The chronic and recurrent nature of these disorders, along with normal laboratory test results, present challenges in their management and ongoing monitoring, which typically focuses on weight changes. Techniques like determining the phase angle using bioimpedance analysis or conducting functional muscle tes...

Objective: Flash glucose monitoring (FGM) allows non-invasive glucose level assessment. Since November 2020 the use of this system is subsidized in patients with type 3c diabetes (DM3c) Our objective was to describe the characteristics of these patients and their glycemic control expressed as times in range.Methods and patients: Observational longitudinal clinical study between January 2021 and December 2021 in patients with DM3c in which FGM implementat...

Objective: Cushing’s disease (CD) is the most common cause of hypercortisolism after iatrogenic origin, it represents approximately 70% of patients with endogenous Cushing’s syndrome (CS) and ectopic ACTH secretion (10%). CD is caused by a corticotropin-secreting pituitary neuroendocrine tumor (ACTH-secreting Pit-NETs), 95% of cases as a microadenoma. In ACTH-dependent CS, differential diagnosis between CD and ectopic CS must be established. 40% of CD cases, any tumo...

Objective: Adrenal venous sampling (AVP) is a reliable procedure to differentiate if in patients with primary aldosteronism (PA) aldosterone production is unilateral or bilateral and guide the treatment of these patients. Our objective was to describe their characteristics and the outcomes of the AVPs.Methods and patients: Observational longitudinal clinical study between July 2020 and September 2021 in patients who underwent AVP in our Hospital.<p c...